Germ-cell hyaluronidases: their roles in sperm function.

@article{MartinDeLeon2011GermcellHT,
  title={Germ-cell hyaluronidases: their roles in sperm function.},
  author={Patricia A Martin-DeLeon},
  journal={International journal of andrology},
  year={2011},
  volume={34 5 Pt 2},
  pages={
          e306-18
        }
}
Hyaluronidases (hyases) are a family of enzymes that catalyse the breakdown of hyaluronic acid (HA), which is abundant in the extracellular matrix. Two unlinked gene clusters encode these six proteins: three each in the somatic (or ubiquitous) acid-active subgroup and the neutral-active germ-cell subgroup. This review analyses the data on the expression and role of hyases in gamete biology and fertilization, using electronic databases until October 2010. Evidence indicates that hyases are… CONTINUE READING

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