Germ‐like cell differentiation from induced pluripotent stem cells (iPSCs)

  title={Germ‐like cell differentiation from induced pluripotent stem cells (iPSCs)},
  author={Zhiwei Niu and Yue Hu and Zhili Chu and Meng Yu and Yaofu Bai and Long Wang and Jinlian Hua},
  journal={Cell Biochemistry and Function},
  • Z. NiuYue Hu J. Hua
  • Published 1 January 2013
  • Biology
  • Cell Biochemistry and Function
Historically, our understanding of molecular genetic aspects of germ cell development has been limited. Recently, results demonstrated that the derivation of pluripotent stem cells may provide the necessary genetic system to study germ cell development. Here, we characterized an induced pluripotent stem cell (iPSC) line, which can spontaneously differentiate into embryonic bodies (EBs) after 3 days of suspension culture, expressing specific markers of three germ layers. Then, we induced the… 

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