Geriatrics: Is There an Association Between Inappropriate Prescription Drug use and Adherence in Discharged Elderly Patients?

@article{Mansur2009GeriatricsIT,
  title={Geriatrics: Is There an Association Between Inappropriate Prescription Drug use and Adherence in Discharged Elderly Patients?},
  author={Nariman Mansur and Avraham Weiss and Yichayaou Beloosesky},
  journal={Annals of Pharmacotherapy},
  year={2009},
  volume={43},
  pages={177 - 184}
}
Background: Inappropriate prescription drug (IPD) use is very common among older patients. However, its impact on medication continuity and adherence after hospitalization has not been researched, with little known regarding readmissions and mortality. Objective: To investigate the prevalence and clinical characteristics of patients discharged with IPDs and examine whether use of these drugs is related to medication continuity and adherence 1 month postdischarge as well as to readmissions and… 
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44 Citations
Background Citations
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Methods Citations
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Results Citations
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44 Citations

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Citation Type

Impact of potentially inappropriate medications and polypharmacy on 3-month readmission among older patients discharged from acute care hospital: a prospective study
TLDR
It is suggested that the association between polypharmacy and 3-month readmission is substantially independent of use of PIMs and hospitalization should always be considered as a clue to individuate unnecessary polyphARMacy and to reduce the burden of medications whenever possible.
The impact of hospitalization on potentially inappropriate prescribing in an acute medical geriatric division
TLDR
Hospitalization in a geriatric division resulted in an increase in PIPs and a decrease in PPOs, and strategies to reduce PIPS need to be implemented, especially for patients with longer hospital stay and a history of falls.
Influence of hospitalization on potentially inappropriate prescribing among elderly patients in a Malaysian community
TLDR
Hospitalization significantly reduces the prevalence of PIMs, but not PPOs or polypharmacy, among elderly patients, whilst high comorbidities and the history of falls were the predictors of discharge PPO.
The effect of hospitalization on potentially inappropriate medication use in older adults with chronic kidney disease
TLDR
Hospitalization was associated with a reduction in PIM use, but there was considerable scope for improvement in these susceptible individuals.
Association between potentially inappropriate medications at discharge and unplanned readmissions among hospitalised elderly patients at a single centre in Japan: a prospective observational study
TLDR
Although the use of PIMs at discharge was not associated with an increased risk of unplanned readmission, given a lack of power of this study due to a low event rate, further studies investigating this association are needed.
Failure to follow medication changes made at hospital discharge is associated with adverse events in 30 days
TLDR
Almost half of all patients were not adherent to some or all changes made to their medications at hospital discharge, and nonadherence to all changes was associated with an increased risk of adverse events.
Potentially Inappropriate Medication in Elderly Hospitalized Patients
TLDR
The evidence pertaining to the application of Beers’ criteria in elderly hospitalized patients is reviewed, while focusing on Italian studies that have investigated the role of PIMs as potential predictors of negative hospital outcomes.
Prevalence of potentially inappropriate medications at admission and discharge among hospitalised elderly patients with acute medical illness at a single centre in Japan: a retrospective cross-sectional study
TLDR
A substantial proportion of hospitalised elderly patients with acute medical illness took PIMs at admission and discharge, and this findings should be confirmed at other hospitals in Japan.
Sex Differences in Inappropriate Drug Use: a Register-Based Study of Over 600,000 Older People
TLDR
The results suggest that neither socioeconomic status nor comorbidity seem to explain sex differences in inappropriate drug use, and women should be monitored separately for women and men.
A Systematic Review of the Impact of Potentially Inappropriate Medication on Health Care Utilization and Costs Among Older Adults
TLDR
PIMs can, in addition to health and quality of life problems, also lead to greater health care service use and, thus, higher health care costs, however, the heterogeneity of the study settings makes the interpretation of the results difficult.
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