Geraniol blocks calcium and potassium channels in the mammalian myocardium: useful effects to treat arrhythmias.

@article{MenezesFilho2014GeraniolBC,
  title={Geraniol blocks calcium and potassium channels in the mammalian myocardium: useful effects to treat arrhythmias.},
  author={Jos{\'e} Evaldo Rodrigues de Menezes-Filho and Ant{\^o}nio Nei Santana Gondim and Jader S. Cruz and Am{\'e}rico Azevedo de Souza and Jos{\'e} Nilson Andrade Dos Santos and Eduardo Ant{\^o}nio Conde-Garcia and Dami{\~a}o Pergentino de Sousa and Michel Santana Santos and Evaleide Diniz de Oliveira and Carla Maria Lins de Vasconcelos},
  journal={Basic & clinical pharmacology & toxicology},
  year={2014},
  volume={115 6},
  pages={534-44}
}
Geraniol is a monoterpene present in several essential oils, and it is known to have a plethora of pharmacological activities. In this study, we explored the contractile and electrophysiological properties of geraniol and its antiarrhythmic effects in the heart. The geraniol effects on atrial contractility, L-type Ca(2+) current, K(+) currents, action potential (AP) parameters, ECG profile and on the arrhythmia induced by ouabain were evaluated. In the atrium, geraniol reduced the contractile… CONTINUE READING
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Geraniol - A review of a commercially important fragrance material

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  • South African Journal of Botany
  • 2010
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