Geosmithia argillacea: an emerging cause of invasive mycosis in human chronic granulomatous disease.

@article{Ravin2011GeosmithiaAA,
  title={Geosmithia argillacea: an emerging cause of invasive mycosis in human chronic granulomatous disease.},
  author={Suk See De Ravin and Malliswari Challipalli and Victoria M. Anderson and Yvonne R. Shea and Beatriz E Marciano and Dianne M Hilligoss and Martha M. Marquesen and Rosamma M Decastro and Yen-Chun Liu and Deanna A. Sutton and Brian L. Wickes and Patricia L Kammeyer and Lynne Sigler and Kathleen Sullivan and Elizabeth M. Kang and Harry L Malech and Steven M Holland and Adrian M. Zelazny},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2011},
  volume={52 6},
  pages={e136-43}
}
BACKGROUND Chronic granulomatous disease (CGD) is an inherited disorder of the nicotinamide adenine dinucleotide phosphate oxidase that leads to defective production of microbicidal superoxide and other oxidative radicals, resulting in increased susceptibility to invasive infections, especially those due to fungi. METHODS Geosmithia argillacea was identified from cultured isolates by genomic sequencing of the internal transcribed spacer region. Isolates previously identified as Paecilomyces… CONTINUE READING

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