Georgia: an unlikely stronghold for bacteriophage therapy

  title={Georgia: an unlikely stronghold for bacteriophage therapy},
  author={Tom Parfitt},
  journal={The Lancet},
  • T. Parfitt
  • Published 25 June 2005
  • Medicine
  • The Lancet
Biocommunication of Phages
Phages have serious effects on global energy and nutrient cycles. Phages actively compete for host. They can distinguish between ‘self’ and ‘non-self’ (complement same, preclude others). They process
Exploiting bacteriophages to tackle Clostridium difficile infection
A continuous model of CDI in a colon model was successfully produced and demonstrated variable efficacy rates from no apparent decrease in the burden of C. difficile to a reduction to below the limit of detection by culture, with no detrimental effect on commensal microbiota.
Acid and aluminium-tolerant microbes isolated from China space station assembly cleanroom surfaces and identified by 16S rRNA/ITS sequencing and MALDI-TOF MS
Abstract Corrosion of aluminium (Al) is a potential problem for spacecraft as this metal is used for various mechanical parts due to its strength, durability, etc. However, it can be corroded by
Exploring the future of infectious disease treatment in a post-antibiotic era: A comparative review of alternative therapeutics.
A comparative review of three promising therapies for antimicrobial oligonucleotides, monoclonal antibodies, and phage therapy seeks to illuminate these promising therapies and encourage the scientific and financial support necessary to usher in the next generation of infectious disease treatment.
Gold—Polyoxoborates Nanocomposite Prohibits Adsorption of Bacteriophages on Inner Surfaces of Polypropylene Labware and Protects Samples from Bacterial and Yeast Infections
It is shown that a BOA nanocomposite deposited onto the inner walls of the containers stabilizes phage suspensions against uncontrolled adsorption and titer decrease and provides antibacterial and antifungal protection.
Phage Therapy in Livestock and Companion Animals
The main recent studies on phage therapy in livestock and companion animals are summarized, providing an insight into current advances in this area and the future of treatments for bacterial infections.
Phages for Africa: The Potential Benefit and Challenges of Phage Therapy for the Livestock Sector in Sub-Saharan Africa
The underlying problems of antibiotic use and resistance associated with livestock farming in SSA, bacteriophages as a suitable alternative, what attributes contribute to making bacteriophile potentially valuable for SSA and recent research on bacteriaphages in Africa are reviewed.
Resistance and Adaptation of Bacteria to Non-Antibiotic Antibacterial Agents: Physical Stressors, Nanoparticles, and Bacteriophages
A detailed overview of how bacteria acquire resistance against non-antibiotic factors is provided and innate bacterial defense systems and how bacteriophages have evolved to tackle them are discussed.