Celebrating eighty years of radionuclide therapy and the work of Saul Hertz
- MedicineJournal of applied clinical medical physics
The work of Hertz and others provided a foundation for the introduction of other radionuclide therapies and for the development of the concept of theranostics, which is a mainstay of therapy for hyperthyroidism and thyroid cancer.
Cerebrospinal fluid drainage kinetics across the cribriform plate are reduced with aging
- Biology, MedicineFluids and barriers of the CNS
The main CSF outflow sites were the nasal region across the cribriform plate and from the spinal regions in mice, and this kinetic approach may have significance in determining early changes in CSF drainage in neurological disorder, age-related cognitive decline and brain diseases.
Atomic Nanogenerators in Targeted Alpha Therapies: Curie’s Legacy in Modern Cancer Management
In this review, the current knowledge on the scientific and clinical background of targeted alpha therapies with atomic in vivo nanogenerators is summarized and open issues and novel approaches with a focus on the future perspective are discussed.
Fluorine-18 Radiolabeling Strategies—Advantages and Disadvantages of Currently Applied Labeling Methods
- BiologyLate-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates
The Chemistry of Imaging Probes
- Biology, Chemistry
It is shown how chemistry can offer molecular imaging the opportunity to express all its potential by exploiting the outstanding possibilities offered by modern synthetic organic and coordination chemistry and the efficient procedures provided by conjugation chemistry.
Początki medycyny nuklearnej w Europie. The development of Nuclear Medicine in Europe.
- Political Science
Artykul przedstawia początki Medycyny Nuklearnej jako jednej najintensywniej ewoluujących dziedzin medycyny, fizyki, chemii oraz inzynierii medycznej. Europejska medycyna nuklearna, ze wzgledu na…
Equilibrium Thermodynamics, Formation, and Dissociation Kinetics of Trivalent Iron and Gallium Complexes of Triazacyclononane-Triphosphinate (TRAP) Chelators: Unraveling the Foundations of Highly Selective Ga-68 Labeling
- ChemistryFront. Chem.
The equilibrium and kinetic properties of [Fe(TR AP)] and [Ga(TRAP)] complexes are remarkably similar due to the close physico-chemical properties of FeIII and GaIII-ions.
Variation of Specific Activities of 68Ga-Aquibeprin and 68Ga-Avebetrin Enables Selective PET Imaging of Different Expression Levels of Integrins α5β1 and αvβ3
- Biology, ChemistryThe Journal of Nuclear Medicine
68Ga-aquibeprin and 68Ga-avebetrin are tracers for selective in vivo mapping of integrins α5β1 and αvβ3, respectively, by PET. Because both tracers exhibit high affinity to their respective targets,…
Development of a hybrid portable medical gamma camera
A novel small field of view medical gamma camera the Compact Gamma Camera (CGC) has been developed at the University of Leicester to provide portable, high-resolution gamma imaging for applications…
Tomographic Reconstruction beyond Classical X-ray CT
For years, simplifying assumptions have been necessary in X-ray Computed Tomography to make the reconstruction of images feasible. Only recently, computer hardware has become powerful enough to…