George E. Brown memorial lecture. Role of atrial peptides in body fluid homeostasis.

Abstract

Extracts of mammalian atria, but not ventricles, induce marked diuresis, natriuresis, and reduction in blood pressure when infused systemically in rats and dogs. These extracts also inhibit aldosterone biosynthesis and renal renin release. Natriuretic peptides, 21 amino acids and longer, have been isolated from atria of rodents and man, and share a nearly… (More)

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@article{Ballermann1986GeorgeEB, title={George E. Brown memorial lecture. Role of atrial peptides in body fluid homeostasis.}, author={Barbara J Ballermann and Barry M. Brenner}, journal={Circulation research}, year={1986}, volume={58 5}, pages={619-30} }