Geometry of the DNA strands within the RecA nucleofilament: role in homologous recombination.

@article{Prvost2003GeometryOT,
  title={Geometry of the DNA strands within the RecA nucleofilament: role in homologous recombination.},
  author={C. Pr{\'e}vost and Masayuki Takahashi},
  journal={Quarterly reviews of biophysics},
  year={2003},
  volume={36 4},
  pages={429-53}
}
Homologous recombination consists of exchanging DNA strands of identical or almost identical sequence. This process is important for both DNA repair and DNA segregation. In prokaryotes, it involves the formation of long helical filaments of the RecA protein on DNA. These filaments incorporate double-stranded DNA from the cell's genetic material, recognize sequence homology and promote strand exchange between the two DNA segments. DNA processing by these nucleofilaments is characterized by large… CONTINUE READING

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