Geometry and network connectivity govern the mechanics of stress fibers.

@article{Kassianidou2017GeometryAN,
  title={Geometry and network connectivity govern the mechanics of stress fibers.},
  author={Elena Kassianidou and Christoph A. Brand and Ulrich S. Schwarz and S. Kiran Kumar},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2017},
  volume={114 10},
  pages={2622-2627}
}
Actomyosin stress fibers (SFs) play key roles in driving polarized motility and generating traction forces, yet little is known about how tension borne by an individual SF is governed by SF geometry and its connectivity to other cytoskeletal elements. We now address this question by combining single-cell micropatterning with subcellular laser ablation to… CONTINUE READING