Geometry and Structural Plasticity of Synaptic Connectivity

  title={Geometry and Structural Plasticity of Synaptic Connectivity},
  author={Armen Stepanyants and Patrick R. Hof and Dmitri B. Chklovskii},
Changes in synaptic connectivity patterns through the formation and elimination of dendritic spines may contribute to structural plasticity in the brain. We characterize this contribution quantitatively by estimating the number of different synaptic connectivity patterns attainable without major arbor remodeling. This number depends on the ratio of the synapses on a dendrite to the axons that pass within a spine length of that dendrite. We call this ratio the filling fraction and calculate it… CONTINUE READING
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