Geometric cue for protein localization in a bacterium.

  title={Geometric cue for protein localization in a bacterium.},
  author={Kumaran S Ramamurthi and Sigol{\`e}ne Lecuyer and Howard A Stone and Richard Losick},
  volume={323 5919},
Proteins in bacteria often deploy to particular places within the cell, but the cues for localization are frequently mysterious. We found that the peripheral membrane protein SpoVM (VM) recognizes a geometric cue when localizing to a particular membrane during sporulation in Bacillus subtilis. Sporulation involves an inner cell maturing into a spore and an outer cell nurturing the developing spore. VM is produced in the outer cell, where it embeds in the membrane that surrounds the inner cell… CONTINUE READING

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Publications referenced by this paper.
Showing 1-10 of 16 references

J. Bacteriol

F O Bendezu, P A De Boer
J. Bacteriol • 2008

Annu. Rev. Microbiol

C Mackenzie
Annu. Rev. Microbiol • 2007

Soft Matter

R Parthasarathy, J T Groves
Soft Matter • 2007

PLoS Comput. Biol

K C Huang, R Mukhopadhyay, N S Wingreen
PLoS Comput. Biol • 2006


A Komeili, Z Li, D K Newman, G J Jensen
Science • 2006

Genes Dev

B Blaylock, X Jiang, A Rubio, C P Moran Jr, K Pogliano
Genes Dev • 2004

Mol. Biol. Cell

E S Seeley, M Kato, N Margolis, W Wickner, G Eitzen
Mol. Biol. Cell • 2002

Proc. Natl. Acad. Sci. U.S.A

D Z Rudner, Q Pan, R M Losick
Proc. Natl. Acad. Sci. U.S.A • 2002

Mol. Microbiol

P Eichenberger, P Fawcett, R Losick
Mol. Microbiol • 2001

Biochim. Biophys. Acta

R S Prajapati, T Ogura, S M Cutting
Biochim. Biophys. Acta • 2000

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