Geometric cue for protein localization in a bacterium.

@article{Ramamurthi2009GeometricCF,
  title={Geometric cue for protein localization in a bacterium.},
  author={Kumaran S Ramamurthi and Sigol{\`e}ne Lecuyer and Howard A Stone and Richard Losick},
  journal={Science},
  year={2009},
  volume={323 5919},
  pages={1354-7}
}
Proteins in bacteria often deploy to particular places within the cell, but the cues for localization are frequently mysterious. We found that the peripheral membrane protein SpoVM (VM) recognizes a geometric cue when localizing to a particular membrane during sporulation in Bacillus subtilis. Sporulation involves an inner cell maturing into a spore and an outer cell nurturing the developing spore. VM is produced in the outer cell, where it embeds in the membrane that surrounds the inner cell… CONTINUE READING

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