Geometric control of the cell cycle.

@article{Martin2009GeometricCO,
  title={Geometric control of the cell cycle.},
  author={Sophie G. Martin},
  journal={Cell cycle},
  year={2009},
  volume={8 22},
  pages={3643-7}
}
How do cells sense their own size and shape? And how does this information regulate progression of the cell cycle? Our group, in parallel to that of Paul Nurse, have recently demonstrated that fission yeast cells use a novel geometry-sensing mechanism to couple cell length perception with entry into mitosis. These rod-shaped cells measure their own length by using a medially-placed sensor, Cdr2, that reads a protein gradient emanating from cell tips, Pom1, to control entry into mitosis. Budding… CONTINUE READING

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