Geometric control of cardiomyogenic induction in human pluripotent stem cells.

@article{Bauwens2011GeometricCO,
  title={Geometric control of cardiomyogenic induction in human pluripotent stem cells.},
  author={C{\'e}line L Bauwens and Hannah W. Song and Nimalan Thavandiran and Mark D. Ungrin and St{\'e}phane Mass{\'e} and Kumaraswamy Nanthakumar and Cheryle A. S{\'e}guin and Peter W. Zandstra},
  journal={Tissue engineering. Part A},
  year={2011},
  volume={17 15-16},
  pages={
          1901-9
        }
}
  • Céline L Bauwens, Hannah W. Song, +5 authors Peter W. Zandstra
  • Published in Tissue engineering. Part A 2011
  • Medicine, Biology
  • Although it has been observed that aggregate size affects cardiac development, an incomplete understanding of the cellular mechanisms underlying human pluripotent stem cell-derived cardiomyogenesis has limited the development of robust defined-condition cardiac cell generation protocols. Our objective was thus to elucidate cellular and molecular mechanisms underlying the endogenous control of human embryonic stem cell (hESC) cardiac tissue development, and to test the hypothesis that hESC… CONTINUE READING

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