Geometric combinatorics and computational molecular biology: branching polytopes for RNA sequences

Abstract

Questions in computational molecular biology generate various discrete optimization problems, such as DNA sequence alignment and RNA secondary structure prediction. However, the optimal solutions are fundamentally dependent on the parameters used in the objective functions. The goal of a parametric analysis is to elucidate such dependencies, especially as… (More)

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@inproceedings{Drellich2015GeometricCA, title={Geometric combinatorics and computational molecular biology: branching polytopes for RNA sequences}, author={Elizabeth Drellich and Andrew Gainer-Dewar and Heather A. Harrington and Qijun He and Christine E. Heitsch and Svetlana Poznanovi'c}, year={2015} }