Geographical structure and differential natural selection among North European populations.

Abstract

Population structure can provide novel insight into the human past, and recognizing and correcting for such stratification is a practical concern in gene mapping by many association methodologies. We investigate these patterns, primarily through principal component (PC) analysis of whole genome SNP polymorphism, in 2099 individuals from populations of… (More)
DOI: 10.1101/gr.083394.108

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@article{McEvoy2009GeographicalSA, title={Geographical structure and differential natural selection among North European populations.}, author={Brian P. McEvoy and Grant W. Montgomery and Allan F. McRae and Samuli Ripatti and Markus Perola and Tim D. Spector and Lynn Cherkas and Kourosh Ahmadi and Dorret I. Boomsma and Gonneke A H M Willemsen and Jouke Jan Hottenga and Nancy L Pedersen and Patrik K. E. Magnusson and Kirsten Ohm Kyvik and Kaare Christensen and Jaakko Kaprio and Kauko V. Heikkil{\"a} and Aarno V Palotie and Elisabeth E Wid{\'e}n and Juha Muilu and Ann-Christine Syv{\"a}nen and Ulrika Liljedahl and Orla Hardiman and Simon Cronin and Leena Peltonen and Nicholas G. Martin and Peter M. Visscher}, journal={Genome research}, year={2009}, volume={19 5}, pages={804-14} }