Geographical Variations in Sex Ratio Trends over Time in Multiple Sclerosis

@inproceedings{Trojano2012GeographicalVI,
  title={Geographical Variations in Sex Ratio Trends over Time in Multiple Sclerosis},
  author={Maria Trojano and Guglielmo Lucchese and Giusi Graziano and Bruce V Taylor and Steve Simpson and Vito Lepore and François Grand’Maison and Pierre Duquette and Guillermo Izquierdo and Pierre Grammond and Maria Pia Amato and Roberto Bergamaschi and Giorgio Giuliani and Cavit Boz and Raymond M. M. Hupperts and Vincent van Pesch and Jeannette Lechner-Scott and Edgardo Cristiano and Marcela P. Fiol and Celia Oreja-Guevara and Mar{\'i}a Laura Saladino and Freek Verheul and Mark Slee and Damiano Paolicelli and Carla Tortorella and Mariangela D’Onghia and Pietro Iaffaldano and Vita Direnzo and Helmut Butzkueven},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND A female/male (F/M) ratio increase over time in multiple sclerosis (MS) patients was demonstrated in many countries around the world. So far, a direct comparison of sex ratio time-trends among MS populations from different geographical areas was not carried out. OBJECTIVE In this paper we assessed and compared sex ratio trends, over a 60-year span, in MS populations belonging to different latitudinal areas. METHODS Data of a cohort of 15,996 (F = 11,290; M = 4,706) definite MS… CONTINUE READING
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