Geographical Genomics of Human Leukocyte Gene Expression Variation in Southern Morocco

@inproceedings{Idaghdour2010GeographicalGO,
  title={Geographical Genomics of Human Leukocyte Gene Expression Variation in Southern Morocco},
  author={Youssef Idaghdour and Wendy Czika and Kevin V. Shianna and Sang Hong Lee and Peter M. Visscher and Hilary C. Martin and Kelci Miclaus and Sami J. Jadallah and David K. Goldstein and Russell D. Wolfinger and Greg Gibson},
  booktitle={Nature Genetics},
  year={2010}
}
Studies of the genetics of gene expression can identify expression SNPs (eSNPs) that explain variation in transcript abundance. Here we address the robustness of eSNP associations to environmental geography and population structure in a comparison of 194 Arab and Amazigh individuals from a city and two villages in southern Morocco. Gene expression differed between pairs of locations for up to a third of all transcripts, with notable enrichment of transcripts involved in ribosomal biosynthesis… CONTINUE READING