Geoepidemiology: the environment and spondyloarthropathies.

  title={Geoepidemiology: the environment and spondyloarthropathies.},
  author={Michael Ehrenfeld},
  journal={Autoimmunity reviews},
  volume={9 5},
Spondyloarthropathies (SPA) are a group of common inflammatory rheumatic disorders characterized by axial and or peripheral arthritis, associated with enthesitis, dactylitis and potential extra-articular manifestations such as uveitis and skin rash. The diseases which comprise the group, share a common genetic predisposition, the HLA-B27 gene, however this association varies markedly among the various SPAs and among different ethnic groups. Environmental factors seem to be triggering the… CONTINUE READING


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