Genus-specific epitope on the 60-kilodalton Legionella heat shock protein recognized by a monoclonal antibody.

@article{Steinmetz1991GenusspecificEO,
  title={Genus-specific epitope on the 60-kilodalton Legionella heat shock protein recognized by a monoclonal antibody.},
  author={Ivo Steinmetz and Claudia Rheinheimer and I G H{\"u}bner and Dieter Bitter-Suermann},
  journal={Journal of clinical microbiology},
  year={1991},
  volume={29 2},
  pages={346-54}
}
A monoclonal antibody (MAb) immunoglobulin G2a (2125) was produced against a 60-kDa Legionella heat shock protein (HSP), recognizing a unique epitope common to all species of the genus Legionella. The antibody reacted in the immunoblot with 59 Legionella species and serogroups that were tested and showed no cross-reactivity with other bacteria, including Acinetobacter spp., Bordetella spp., Pseudomonas spp., Mycobacterium spp., and Escherichia coli. Two other MAbs (2122 and 2130) reacted with… CONTINUE READING
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