Genotyping of three single nucleotide polymorphisms following whole genome preamplification of DNA collected from buccal cells.

@article{Haberstick2004GenotypingOT,
  title={Genotyping of three single nucleotide polymorphisms following whole genome preamplification of DNA collected from buccal cells.},
  author={Brett C. Haberstick and Andrew Smolen},
  journal={Behavior genetics},
  year={2004},
  volume={34 5},
  pages={541-7}
}
Collection of genomic DNA from buccal cells is a simple and convenient procedure for genotyping individuals. One disadvantage is that the amount of genomic DNA may be inadequate for genotyping projects that require a large number of determinations per sample. Primer Extension Preamplification (PEP) methods that can amplify the entire genome 100-fold or more offer a potential solution to this problem. To test whether the preamplified DNA product retains the original allelic distribution of the… CONTINUE READING

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