Genotyping in the MHC locus: potential for defining predictive markers in sarcoidosis

Abstract

In sarcoidosis, host genetic factors are discussed as contributing to disease susceptibility and course. Since tumor necrosis factor (TNF)-alpha is a central mediator of granuloma formation and since elevated TNF-alpha levels are found during active phases of sarcoidosis, genetic polymorphisms correlating with influences on TNF-alpha levels are of special… (More)

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Cite this paper

@article{Seitzer2002GenotypingIT, title={Genotyping in the MHC locus: potential for defining predictive markers in sarcoidosis}, author={Ulrike Seitzer and Johannes Gerdes and Joachim M{\"u}ller-Quernheim}, journal={Respiratory Research}, year={2002}, volume={3}, pages={6 - 6} }