Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies.

@article{Abnet2012GenotypicVA,
  title={Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies.},
  author={Christian C Abnet and Zhaoming Wang and Xin Song and Nan Hu and Fu-you Zhou and Neal D Freedman and Xue-Min Li and Kai Sing Yu and Xiao-Ou Shu and J. Yuan and Wei Zheng and Sanford S M Dawsey and Linda M. Liao and Maxwell P. Lee and Ti Ming Ding and Yawei Qiao and Yu-tang Gao and Woon Puay Koh and Yong Bing Xiang and Ze-Zhong Tang and Jin-hu Fan and Charles Y. C. Chung and Chaoyu Wang and William Wheeler and Meredith Yeager and Jeff Yuenger and Amy Joy Hutchinson and Kevin Bruce Jacobs and Carol A Giffen and Laurie A. Burdett and Joseph F. Fraumeni and Margaret Anne Tucker and Wong Ho Chow and Xue-ke Zhao and Jiang-man Li and Aili Li and Liang-dan Sun and Wu Ji Wei and Ji-lin Li and Ping Zhang and Hong-Lei Li and Wen-yan Cui and Wei-peng Wang and Zhi-cai Liu and Xiaojing Yang and Wen-jing Fu and Ji-li Cui and Hong-Li Lin and Wen-liang Zhu and Min Liu and Xi Chen and Jie Chen and Li Tong Guo and Jing-Jing Han and Sheng-li Zhou and Jia Huang and Yuehua Wu and Chao Yuan and Jing Huang and Ai-fang Ji and Jian-Wei Kul and Zhong-min Fan and Jian-Po Wang and Dong-yun Zhang and Lian-qun Zhang and Wei Zhang and Yuan-Fang Chen and Jing-li Ren and Xiu-min Li and Jin-Cheng Dong and Guo-lan Xing and Zhi-Gang Guo and Jian-xue Yang and Yi-ming Mao and Yuan Yuan and Er-Tao Guo and Zhi-Chao Hou and Jing Liu and Yan Li and Sa Tang and Jia Min Chang and Xiu-Qin Peng and Min Han and Wan-Li Yin and Ya-li Liu and Yan-Long Hu and Yu Liu and Liu-qin Yang and Fu-Guo Zhu and Xiu-feng Yang and Xiao-Shan Feng and Z. G. Wang and Yin Li and She-gan Gao and Hai-Lin Liu and Ling Yuan and Yingyu Jin and Yan-Rui Zhang and Ilyar Sheyhidin and Feng Li and Bao-ping Chen and Shu-wei Ren and Bin Liu and D Li and Gao-Fu Zhang and Wen-Bin Yue and Chang-wei Feng and Qirenwang Qige and Jian-Ting Zhao and Wen-jun Yang and Guang-yan Lei and Long-qi Chen and En-Min Li and Li-Yan Xu and Zhi-yong Wu and Zhi-Qin Bao and J. Chen and Xian-Chang Li and Xiang Zhuang and Ying-Fa Zhou and Xian-bo Zuo and Zi-ming Dong and Lu-Wen Wang and Xue-Pin Fan and Jin Wang and Qi Zhou and Guo-Shun Ma and Qin-xian Zhang and Hai Liu and Xin-Ying Jian and Sin-Yong Lian and Jin-sheng Wang and Fu-Bao Chang and Chang-dong Lu and Jian-Jun Miao and Zhi-Guo Chen and Ran Wang and Ming Guo and Zeng-Lin Fan and Ping Kee Tao and Tai-Jing Liu and J C Wei and Lei Fan and Xian-Zeng Wang and Fu-sheng Gao and Tian-Yun Wang and Dong Xie and Li Wang and Shu-Qing Chen and Wan-cai Yang and Jun-yan Hong and Liang Wang and Song-Liang Qiu and Alisa M Goldstein and Zhi-Qing Yuan and Stephen J. Chanock and Xue-jun Zhang and Philip R. Taylor and Li-dong Wang},
  journal={Human molecular genetics},
  year={2012},
  volume={21 9},
  pages={
          2132-41
        }
}
Genome-wide association studies have identified susceptibility loci for esophageal squamous cell carcinoma (ESCC). We conducted a meta-analysis of all single-nucleotide polymorphisms (SNPs) that showed nominally significant P-values in two previously published genome-wide scans that included a total of 2961 ESCC cases and 3400 controls. The meta-analysis revealed five SNPs at 2q33 with P< 5 × 10(-8), and the strongest signal was rs13016963, with a combined odds ratio (95% confidence interval… CONTINUE READING
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