Genotypic analysis of the earliest known prehistoric case of tuberculosis in Britain.

  title={Genotypic analysis of the earliest known prehistoric case of tuberculosis in Britain.},
  author={G. Michael Taylor and Douglas Brownlee Young and Simon Mays},
  journal={Journal of clinical microbiology},
  volume={43 5},
The earliest known case of human tuberculosis in Britain dates to the middle period of the Iron Age, approximately 2,200 years before present. Bone lesions on the spine of a male skeleton excavated at Tarrant Hinton in Dorset, United Kingdom, show evidence of Pott's disease and are supported by molecular evidence of Mycobacterium tuberculosis complex DNA amplified by IS6110 PCR (19). In the present study, we used a further series of sensitive PCR methods to confirm the diagnosis of tuberculosis… CONTINUE READING
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