Genotype specific age related changes in a transgenic rat model of Huntington's disease

Abstract

We aimed to characterize the transgenic Huntington rat model with in vivo imaging and identify sensitive and reliable biomarkers associated with early and progressive disease status. In order to do so, we performed a multimodality (DTI and PET) longitudinal imaging study, during which the same TgHD and wildtype (Wt) rats were repetitively scanned… (More)
DOI: 10.1016/j.neuroimage.2011.07.007

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