Genotype prediction using a dense map of SNPs.

  title={Genotype prediction using a dense map of SNPs.},
  author={David M. Evans and Lon R. Cardon and Andrew P. Morris},
  journal={Genetic epidemiology},
  volume={27 4},
The International Haplotype Mapping Project (HapMap) aims to characterize the distribution and extent of linkage disequilibrium (LD) throughout the human genome, thereby facilitating genome-wide association analysis and the search for the genetic determinants of complex diseases. Implicit in the rationale behind the project is the expectation that hidden (unobserved) disease-causing variants will be in significant LD with surrounding typed markers and will thus be amenable to detection using… CONTINUE READING

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