Genotype mixtures of hepatitis B virus in patients treated with interferon.

@article{Hannoun2002GenotypeMO,
  title={Genotype mixtures of hepatitis B virus in patients treated with interferon.},
  author={Charles Hannoun and Kim Krogsgaard and Peter Horal and Magnus Lindh},
  journal={The Journal of infectious diseases},
  year={2002},
  volume={186 6},
  pages={752-9}
}
Little is known about coinfection among several hepatitis B virus (HBV) genotypes, although previous reports of recombination and genotype shifts indicate that this should occur. In the present study, we designed a method to identify mixtures of genotype A and another genotype, regardless of whether one of them predominates. Using this method, signs of genotypic coinfection were found in 20 (67%) of 30 hepatitis B e antigen-positive patients treated with interferon (IFN). In 8 of these patients… CONTINUE READING