Genotype link with extreme antisocial behavior: the contribution of cognitive pathways.

  title={Genotype link with extreme antisocial behavior: the contribution of cognitive pathways.},
  author={Kate Langley and Jon Heron and Michael C O'Donovan and Michael J. Owen and Anita Thapar},
  journal={Archives of general psychiatry},
  volume={67 12},
CONTEXT As genes associated with common disorders are increasingly identified, we need to progress from observing associations to identifying risk pathways. The high-activity COMT genotype, in the presence of attention-deficit/hyperactivity disorder (ADHD), has previously been shown to be associated with extreme antisocial behavior. The same genotype has also been implicated in affecting cognitive function in healthy individuals. Impaired cognitive function might therefore lie on the risk… CONTINUE READING
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