Genotype determines phenotype in experimental Lyme borreliosis.

  title={Genotype determines phenotype in experimental Lyme borreliosis.},
  author={Andrew R. Pachner and Donna Dail and Yunhong Bai and Marie Sondey and Lena Pak and Kavitha Narayan and Diego Cadavid},
  journal={Annals of neurology},
  volume={56 3},
Borrelia burgdorferi sensu lato, the causative organism of Lyme borreliosis, is a heterogeneous group of spirochetes, consisting of at least three pathogenic species. To test the hypothesis that the genetic heterogeneity is the reason for the clinical differences, we investigated whether the experimental disease induced by European isolates is different from that induced by American isolates. Two American isolates of species B. burgdorferi sensu stricto were compared with three European… CONTINUE READING

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