Genotype and allele frequencies of N-acetyltransferase 2 and glutathione S-transferase in the Iranian population.

@article{TorkamanBoutorabi2007GenotypeAA,
  title={Genotype and allele frequencies of N-acetyltransferase 2 and glutathione S-transferase in the Iranian population.},
  author={Anahita Torkaman-Boutorabi and Mahmood Hoormand and Naser Naghdi and Masoomeh Bakhshayesh and Iraj Milanian},
  journal={Clinical and experimental pharmacology & physiology},
  year={2007},
  volume={34 11},
  pages={1207-11}
}
1. Xenobiotic-metabolizing enzymes constitute an important line of defence against a variety of carcinogens. Many are polymorphic, constituting the basis for the wide interindividual variation in metabolic capacity and possibly a source of variation in the susceptibility to chemical-induced carcinogenesis. The aim of the present study was to determine the frequencies of important allelic variants in the N-acetyltransferase 2 (NAT2) and glutathione S-transferase (GST) genes in the Iranian… CONTINUE READING