Genotoxicity of quercetin in cultured mammalian cells.

@article{Hoeven1984GenotoxicityOQ,
  title={Genotoxicity of quercetin in cultured mammalian cells.},
  author={J. V. D. van der Hoeven and I. Bruggeman and F. Debets},
  journal={Mutation research},
  year={1984},
  volume={136 1},
  pages={
          9-21
        }
}
The naturally occurring flavonol, quercetin, was investigated concerning its ability to induce SCEs and HGPRT-deficient mutants in V79 Chinese hamster cells, and HGPRT- and TK-deficient mutants in mouse lymphoma L5178Y cells. V79 cells were exposed to quercetin in monolayer, under exponential growing condition, in suspension in the presence of liver homogenate, and in co-cultivation with primary chick embryo hepatocytes. No induction of HGPRT-deficient mutants was observed. Furthermore, under… Expand
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