Genotoxicity of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQ™).

@article{Nakano2013GenotoxicityOP,
  title={Genotoxicity of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQ™).},
  author={Masahiko Nakano and Hiroaki Suzuki and Tadashi Imamura and Annette Anling Lau and Barry G. Lynch},
  journal={Regulatory toxicology and pharmacology : RTP},
  year={2013},
  volume={67 2},
  pages={
          189-97
        }
}
The genotoxic potential of pyrroloquinoline quinone (PQQ) disodium salt (BioPQQ™) was evaluated in a battery of genotoxicity tests. The results of the bacterial mutation assay (Ames test) were negative. Weak positive results were obtained in 2 separate in vitro chromosomal aberration test in Chinese hamster lung (CHL) fibroblasts. Upon testing in an in vitro chromosomal aberration test in human peripheral blood lymphocytes, no genotoxic activity of PQQ was noted. In the in vivo micronucleus… CONTINUE READING

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Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice.

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  • 2017
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A subchronic oral toxicity study on pyrroloquinoline quinone (PQQ) disodium salt in rats.

  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2015
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CITES METHODS & BACKGROUND

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