Genotoxicity of acrylamide in human hepatoma G2 (HepG2) cells.

  title={Genotoxicity of acrylamide in human hepatoma G2 (HepG2) cells.},
  author={Liping Jiang and Jun Cao and Yu An and Chengyan Geng and Shuxian Qu and Lijie Jiang and Laifu Zhong},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  volume={21 8},
The recent finding that acrylamide (AA), a carcinogen in animal experiments and a probable human carcinogen, is formed in foods during cooking raises human health concerns. The relevance of dietary exposure for humans is still under debate. The purpose of the study was to evaluate the possible genotoxicity of acrylamide in human hepatoma G2 (HepG2) cells, a cell line of great relevance to detect genotoxic/antigenotoxic substances, using single cell gel electrophoresis (SCGE) assay and… CONTINUE READING


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