Genotoxicity induced by nerol, an essential oil present in citric plants using human peripheral blood mononuclear cells (PBMC) and HepG2/C3A cells as a model

@article{Silva2021GenotoxicityIB,
  title={Genotoxicity induced by nerol, an essential oil present in citric plants using human peripheral blood mononuclear cells (PBMC) and HepG2/C3A cells as a model},
  author={Brian Ogushi Silva and Juliana Botinhon Orlando and Camila Lehnhardt Pires and Cl{\'e}lia Akiko Hiruma-Lima and Isabel O'Neill de Mascarenhas Gaiv{\~a}o and F{\'a}bio F. Perazzo and Edson Luis Maistro},
  journal={Journal of Toxicology and Environmental Health, Part A},
  year={2021},
  volume={84},
  pages={518 - 528}
}
ABSTRACT Nerol (cis-3,7-dimethyl-2,6-octadien-1-ol) is a monoterpene widely used in cosmetic products, household detergents and cleaners, as well as a flavoring in several food products. Despite the high level of human exposure to nerol, an absence of studies regarding potential genetic toxicity in human cells exists. The aim of this investigation was to examine the cytotoxic and genotoxic potential of this monoterpene on human peripheral blood mononuclear cells as well as hepatic metabolizing… 
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Risk assessment of in vitro cytotoxicity, antioxidant and antimicrobial activities of Mentha piperita L. essential oil.
TLDR
Data suggest that in presence of the essential oil of Mentha piperita L. (peppermint), antioxidant, antibacterial, antitumor and non-cytotoxic properties were noted.

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