Genotoxicity biomarkers' association with B(a)P biotransformation in Dicentrarchus labrax L.

@article{Gravato2003GenotoxicityBA,
  title={Genotoxicity biomarkers' association with B(a)P biotransformation in Dicentrarchus labrax L.},
  author={Carlos S Gravato and Maria Ana Santos},
  journal={Ecotoxicology and environmental safety},
  year={2003},
  volume={55 3},
  pages={352-8}
}
Dicentrarchus labrax (sea bass) were exposed during 0, 4, 8, 16, 24, 48, and 96 h to 0 and 0.1 microM benzo(a)pyrene (B(a)P), an environmental pollutant, and the following biomarkers were measured: (1) liver cytochrome P450 (P450) content and ethoxyresorufin-O-deethylase (EROD) activity as phase I biotransformation parameters, (2) liver gluthathione-S-transferase (GST) activity as a phase II biotransformation conjugation enzyme, (3) biliary and liver cytosolic B(a)P-type metabolites by fixed… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…