Genotoxicity and mutagenicity induced by acute crack cocaine exposure in mice

  title={Genotoxicity and mutagenicity induced by acute crack cocaine exposure in mice},
  author={Ver{\^o}nica Quispe Yujra and Eduardo Gregolin Moretti and Samuel Rangel Cl{\'a}udio and Marcelo Jos{\'e} Dias Silva and Flavia de Oliveira and Celina Tizuko Fujiyama Oshima and Daniel Araki Ribeiro},
  journal={Drug and Chemical Toxicology},
  pages={388 - 391}
Abstract Context: Crack cocaine is an illicit drug derived from cocaine, in which use and abuse have increased around the world, especially in developing countries. Objectives: The aim of this study was to evaluate genomic damage in multiple organs of mice following acute exposure to crack cocaine. For this purpose, single cell gel (comet) assay in peripheral blood, liver, kidney, and brain cells was performed and micronucleus test for bone narrow and liver cells was also made in this setting… 
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