Genotoxicity and cytotoxicity of cisplatin treatment combined with anaesthetics on EAT cells in vivo.


In this study, DNA damage in tumour cells, as well as irreversible cell damage leading to apoptosis induced in vivo by the combined application of cisplatin and inhalation anaesthetics, was investigated. The genotoxicity of anaesthetics on Ehrlich ascites tumour (EAT) cells of mice, alone or in combined application with cisplatin, was estimated by using the… (More)
DOI: 10.1159/000218066


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