Genotoxic risk and oxidative DNA damage in HepG2 cells exposed to perfluorooctanoic acid.

@article{Yao2005GenotoxicRA,
  title={Genotoxic risk and oxidative DNA damage in HepG2 cells exposed to perfluorooctanoic acid.},
  author={Xiaofeng Yao and Laifu Zhong},
  journal={Mutation research},
  year={2005},
  volume={587 1-2},
  pages={38-44}
}
Perfluorooctanoic acid (C8HF15O2, PFOA) is widely used in various industrial fields for decades and it is environmentally bioaccumulative. PFOA is known as a potent hepatocarcinogen in rodents. But it is not yet clear whether it is also carcinogenic in humans, and the genotoxic effects of PFOA on human cells have not yet been examined. In this study, the… CONTINUE READING