Genotoxic potential of Cotinus coggygria Scop. (Anacardiaceae) stem extract in vivo

@inproceedings{Mati2011GenotoxicPO,
  title={Genotoxic potential of Cotinus coggygria Scop. (Anacardiaceae) stem extract in vivo},
  author={Sanja Lj Mati{\'c} and Sne{\vz}ana M Stani{\'c} and Desanka B Bogojevi{\'c} and Slavica R. Solujic and Nevena Grdovi{\'c} and Melita Vidakovi{\'c} and Mirjana Mihailovi{\'c}},
  booktitle={Genetics and molecular biology},
  year={2011}
}
The intention was to evaluate the possible in vivo genotoxic potential in different cell-types, of a methanol extract obtained from the plant stem of Cotinus coggygria Scop., using the sex-linked recessive lethal (or SLRL) test and alkaline comet assay. The SLRL test, revealed the genotoxic effect of this extract in postmeiotic and premeiotic germ-cell lines. The comet assay was carried out on rat liver and bone marrow at 24 and 72 h after intraperitoneal administration. For genotoxic… CONTINUE READING

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