Genotoxic effects on human spermatozoa among pesticide factory workers exposed to fenvalerate.

  title={Genotoxic effects on human spermatozoa among pesticide factory workers exposed to fenvalerate.},
  author={Yankai Xia and Qian Bian and Lichun Xu and Senping Cheng and Ling Song and Jiayin Liu and Wei Wu and Shoulin Wang and Xinru Wang},
  volume={203 1-3},

Genotoxic effects on spermatozoa of carbaryl-exposed workers.

The findings suggested that carbaryl might induce morphologic abnormalities and genotoxic defects of spermatozoa among exposed workers by causing DNA fragmentation and numerical CA in spermatogenesis as a potential genot toxicant.

Human semen quality and sperm DNA damage in relation to urinary metabolites of pyrethroid insecticides.

Evidence for reduced semen quality and increased sperm DNA damage in relation to urinary metabolites of pyrethroid insecticides is found, and may be of concern due to increased pyrethoid use and prevalent human exposure.

Effects of the pesticide cyren on chromosomes and sperms of albino males mice.

Evaluating the genotoxicity of this insecticide in males of Swiss albino mice Mus musculus BALB/c strain revealed that Cyren has the ability to induce sperm abnormalities in all doses used compared to untreated mice.

Pesticides and the induction of aneuploidy in human sperm

The available data indicates that at least some of the commonly used pesticides are capable of inducing aneuploidy in human sperm when the exposure level is high enough.

Lambda, the pyrethroid insecticide as a mutagenic agent in both somatic and germ cells.

The present study clearly indicates that Cyhalothrin (lambda) insecticide is genotoxic to the different kinds of cells analyzed and much more care should be taken during the use of these pesticides.

Fenvalerate, A Pyrethroid Insecticide, Adversely Affects Sperm Production and Storage in Male Rats

Data suggest that fenvalerate treatment in this study failed to compromise fertility, possibly due to enhanced reproductive capacity in rodents compared to humans.

Mutagenic biomonitoring of pirethroid insecticides in human lymphocyte cultures: Use of micronuclei as biomarkers and recovery by Rosa canina extracts of mutagenic effects

It is concluded that cypermethrin and fenvalerate have genotoxic effects, the water and ethanol extracts of rosehip reduced the genotoxicity of the both insecticides.

Environmental exposure to pyrethroids and sperm sex chromosome disomy: a cross-sectional study

The findings suggest that urinary concentrations of CDCCA and TDCCA above the LOD were associated with increased rates of aneuploidy, however the findings for 3BPA were not consistent.

Environmental Exposure to Polychlorinated Biphenyls and p,p´-DDE and Sperm Sex-Chromosome Disomy

The findings suggest that exposure to p,p´-DDE may be associated with increased rates of XX, XY, and total sex-chromosome disomy, whereas exposure to PCBs may beassociated withIncreased rates of YY, XY; and totalSex- Chromosome Disomy.



Organophosphorous pesticide exposure increases the frequency of sperm sex null aneuploidy.

Poisson regression analysis adjusted for age, alcohol intake, and sperm concentration showed significant associations between OP metabolite concentrations and increased frequency of sperm aneuploidies, and the risk for genetic syndromes, such as Turner's.

Steroidogenic alterations in testes and sera of rats exposed to formulated Fenvalerate by inhalation

The results for the first time indicate the role of testosterone in Fen (20% EC)-induced male reproductive toxicity of rats subchronically exposed by inhalation probably due to neuroendocrine-mediated phenomenon and hormone-disrupting property of the insecticide.

Aneuploidy in sperm and exposure to fungicides and lifestyle factors

The present study supports earlier ones showing that smoking can increase aneuploidy in human sperm and suggests that the sensitivity of the sperm‐FISH method may not be sufficient for low‐level exposures.

Sperm aneuploidy among Chinese pesticide factory workers: scoring by the FISH method.

It is concluded that occupational exposure to organophosphate pesticides moderately increases the prevalence of sperm aneuploidy among pesticide factory workers in Anhui, China.

Analysis of cytogenetic damage induced in CHO cells by the pyrethroid insecticide fenvalerate.

Results indicate that fenvalerate in the presence of S9-mix is able significantly to increase the frequency of CA, while in the SCE test this increase occurred both in the Presence and in the absence of a rat liver activation system.

Numerical Chromosomal Abnormalities in Rat Epididymal Spermatozoa Following Chronic Cyclophosphamide Exposure1

Cyclophosphamide disrupts meiotic events before pachynema during spermatogenesis, emphasizing the potential for adverse progeny outcomes following genotoxic damage.