Genotoxic effects on human spermatozoa among pesticide factory workers exposed to fenvalerate.

@article{Xia2004GenotoxicEO,
  title={Genotoxic effects on human spermatozoa among pesticide factory workers exposed to fenvalerate.},
  author={Yankai Xia and Qian Bian and Lichun Xu and Senping Cheng and Ling Song and Jiayin Liu and Wei Wu and Shoulin Wang and Xinru Wang},
  journal={Toxicology},
  year={2004},
  volume={203 1-3},
  pages={
          49-60
        }
}
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100 Citations
Highly Influential Citations
5
Background Citations
43
Methods Citations
2
Results Citations
3

100 Citations

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Evidence for reduced semen quality and increased sperm DNA damage in relation to urinary metabolites of pyrethroid insecticides is found, and may be of concern due to increased pyrethoid use and prevalent human exposure.

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Lambda, the pyrethroid insecticide as a mutagenic agent in both somatic and germ cells.

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Fenvalerate, A Pyrethroid Insecticide, Adversely Affects Sperm Production and Storage in Male Rats

Data suggest that fenvalerate treatment in this study failed to compromise fertility, possibly due to enhanced reproductive capacity in rodents compared to humans.

Effect of low-dose fenvalerate on semen quality capacitation in adult mice.

Exposure to low-dose FEN for 30 days reduces semen quality and sperm capacitation in adult mice and reduces the rate of mouse sperm capacitations in a dose-dependent manner.

Mutagenic biomonitoring of pirethroid insecticides in human lymphocyte cultures: Use of micronuclei as biomarkers and recovery by Rosa canina extracts of mutagenic effects

It is concluded that cypermethrin and fenvalerate have genotoxic effects, the water and ethanol extracts of rosehip reduced the genotoxicity of the both insecticides.

Effects of non-occupational environmental exposure to pyrethroids on semen quality and sperm DNA integrity in Chinese men.

Environmental exposure to pyrethroids and sperm sex chromosome disomy: a cross-sectional study

The findings suggest that urinary concentrations of CDCCA and TDCCA above the LOD were associated with increased rates of aneuploidy, however the findings for 3BPA were not consistent.

Environmental Exposure to Polychlorinated Biphenyls and p,p´-DDE and Sperm Sex-Chromosome Disomy

The findings suggest that exposure to p,p´-DDE may be associated with increased rates of XX, XY, and total sex-chromosome disomy, whereas exposure to PCBs may beassociated withIncreased rates of YY, XY; and totalSex- Chromosome Disomy.
...

References

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