Genotoxic differences by sex in nasal epithelium and blood leukocytes in subjects residing in a highly polluted area.

@article{Fortoul2004GenotoxicDB,
  title={Genotoxic differences by sex in nasal epithelium and blood leukocytes in subjects residing in a highly polluted area.},
  author={Teresa I Fortoul and Mahara Valverde and Mar{\'i}a Cecilia Hincapi{\'e} L{\'o}pez and Mar{\'i}a Rosa Avila-Costa and Ma Carmen Avila-Casado and Patricia Mussali-Galante and Adriana Elizabeth Gonz{\'a}lez-Villalva and Emilio Rojas and Patricia Ostrosky-Shejet},
  journal={Environmental research},
  year={2004},
  volume={94 3},
  pages={
          243-8
        }
}
We describe differences by sex in genotoxic damage found in a population of medical students exposed to a highly oxidative atmosphere, compared with a control group, measured by the single-cell gel electrophoresis assay and histological changes in nasal epithelium smears. Cells were obtained from the nasal epithelium and blood leukocytes. Higher DNA damage in nasal cells and leukocytes was found in males compared to females and control subjects. The percentage of squamous metaplastic changes in… CONTINUE READING
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