Genotoxic Evaluation of Surfactin C in Chinese Hamster Lung Cell Line

@article{Lim2009GenotoxicEO,
  title={Genotoxic Evaluation of Surfactin C in Chinese Hamster Lung Cell Line},
  author={J. H. Lim and I. B. Song and B. Park and M. Kim and Y. Hwang and H. I. Yun},
  journal={Toxicological Research},
  year={2009},
  volume={25},
  pages={47 - 50}
}
  • J. H. Lim, I. B. Song, +3 authors H. I. Yun
  • Published 2009
  • Biology, Medicine
  • Toxicological Research
  • To investigate the mutation inducibility of surfactin C, we performed the chromosome aberration assay with Chinese hamster lung cells in vitro. The colorimetric MTT screening assay was carried out to determine the cytotoxicity index (IC50) of surfactin C. The IC50 value was 125 μg/ml. For the chromosome aberration test of surfactin C, the maximum concentration was employed as 125 μg/ml, followed by 62.5 and 31.25 μg/ml for the lower concentrations, with or without metabolic activation (S9… CONTINUE READING
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