Genotoxic Effect of Furazolidone, an Anti-Diarrhoeal Drug on the Root Meristem of Allium cepa L

  • Anu Annamma Mammen
  • Published 2010

Abstract

The present work was conducted to study the genotoxic effect of Furazolidone, an anti-diarrhoeal drug. Onion root meristems were cultured and analyzed after exposure to different time periods to the drug. There was a time-dependent decrease in mitotic indices and an increase in chromosomal anomalies compared to the control. Cell division was completely arrested after 24 hours of incubation with 0.05% Furazolidone. This study proves the genotoxic effect of Furazolidone and emphasizes the prevention of the use of this drug in medicine. _____________________________________________________________________________________________________________

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Cite this paper

@inproceedings{Mammen2010GenotoxicEO, title={Genotoxic Effect of Furazolidone, an Anti-Diarrhoeal Drug on the Root Meristem of Allium cepa L}, author={Anu Annamma Mammen}, year={2010} }