Genomics of human intracranial aneurysm wall.

  title={Genomics of human intracranial aneurysm wall.},
  author={Changbin Shi and I A Awad and Nadereh Jafari and Simon Lin and Pan Du and Ziad A. Hage and Robert Shenkar and Christopher C. Getch and Markus Bredel and H. Hunt Batjer and Bernard R. Bendok},
  volume={40 4},
BACKGROUND AND PURPOSE The pathogenesis of intracranial aneurysms (IAs) remains elusive. Most studies have focused on individual genes, or a few interrelated genes or products, at a time in human IA. However, a broad view of pathologic mechanisms has not been investigated by identifying pathogenic genes and their interaction in networks. Our study aimed to analyze global gene expression patterns in the IA wall. METHODS To our knowledge, our group was the first to perform Illumina microarray… CONTINUE READING


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