Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool.

@article{Schlter2007GenomicsOI,
  title={Genomics of IncP-1 antibiotic resistance plasmids isolated from wastewater treatment plants provides evidence for a widely accessible drug resistance gene pool.},
  author={Andreas Schl{\"u}ter and Rafael Szczepanowski and Alfred P{\"u}hler and Eva M Top},
  journal={FEMS microbiology reviews},
  year={2007},
  volume={31 4},
  pages={449-77}
}
The dramatic spread of antibiotic resistance is a crisis in the treatment of infectious diseases that affect humans. Several studies suggest that wastewater treatment plants (WWTP) are reservoirs for diverse mobile antibiotic resistance elements. This review summarizes findings derived from genomic analysis of IncP-1 resistance plasmids isolated from WWTP bacteria. Plasmids that belong to the IncP-1 group are self-transmissible, and transfer to and replicate in a wide range of hosts. Their… CONTINUE READING
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