Genomics in clinical practice: lessons from the front lines.


The price of whole-genome and -exome sequencing has fallen to the point where these methods can be applied to clinical medicine. Here, we outline the lessons we have learned in converting a sequencing laboratory designed for research into a fully functional clinical program.

DOI: 10.1126/scitranslmed.3006468

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@article{Jacob2013GenomicsIC, title={Genomics in clinical practice: lessons from the front lines.}, author={Howard J. Jacob and Kelly J Abrams and David Bick and Kent Brodie and David P Dimmock and Michael H. Farrell and Jennifer L. Geurts and Jeremy M Harris and Daniel C Helbling and Barbara J. Joers and Robert M Kliegman and George Kowalski and Jozef Lazar and David A. Margolis and Paula E. North and Jill Northup and Altheia Roquemore-Goins and Gunter H. Scharer and Mary Shimoyama and Kimberly A Strong and Bradley Taylor and Shirng-wern Tsaih and Michael R. Tschannen and Regan L. Veith and Jaime Wendt-Andrae and Brandon M Wilk and Elizabeth A. Worthey}, journal={Science translational medicine}, year={2013}, volume={5 194}, pages={194cm5} }