Genomics and transcriptomics in drug discovery.

@article{Dopazo2014GenomicsAT,
  title={Genomics and transcriptomics in drug discovery.},
  author={Joaqu{\'i}n Dopazo},
  journal={Drug discovery today},
  year={2014},
  volume={19 2},
  pages={126-32}
}
The popularization of genomic high-throughput technologies is causing a revolution in biomedical research and, particularly, is transforming the field of drug discovery. Systems biology offers a framework to understand the extensive human genetic heterogeneity revealed by genomic sequencing in the context of the network of functional, regulatory and physical protein-drug interactions. Thus, approaches to find biomarkers and therapeutic targets will have to take into account the complex system… CONTINUE READING
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