Genomics and gene transcription kinetics in yeast.

  title={Genomics and gene transcription kinetics in yeast.},
  author={Jos{\'e} E. P{\'e}rez-Ort{\'i}n and Paula M. Alepuz and Joaqu{\'i}n Moreno},
  journal={Trends in genetics : TIG},
  volume={23 5},
As an adaptive response to new conditions, mRNA concentrations in eukaryotes are readjusted after any environmental change. Although mRNA concentrations can be modified by altering synthesis and/or degradation rates, the rapidity of the transition to a new concentration depends on the regulation of mRNA stability. There are several plausible transcriptional strategies following environmental change, reflecting different degrees of compromise between speed of response and cost of synthesis. The… CONTINUE READING

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