Genomics: RNA detection with C2c2

  title={Genomics: RNA detection with C2c2},
  author={Richard Pattison},
  journal={Nature Methods},
The discovery of two distinct endonuclease activities in the C2c2 protein explains how template RNAs are processed in type VI CRISPR systems and enables the development of a sensitive RNA detection system. In the bacterial adaptive immune system, clustered, regularly interspaced short palindromic repeats (CRISPRs) direct cleavage of target nucleic acids… CONTINUE READING