Genomic variation among contemporary Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients.

@article{Chung2012GenomicVA,
  title={Genomic variation among contemporary Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients.},
  author={Jade C. S. Chung and Jennifer Becq and Louise Fraser and Ole Schulz-Trieglaff and Nicholas J. Bond and Juliet E Foweraker and Kenneth Deans Bruce and Geoffrey P. Smith and Martin Welch},
  journal={Journal of bacteriology},
  year={2012},
  volume={194 18},
  pages={4857-66}
}
The airways of individuals with cystic fibrosis (CF) often become chronically infected with unique strains of the opportunistic pathogen Pseudomonas aeruginosa. Several lines of evidence suggest that the infecting P. aeruginosa lineage diversifies in the CF lung niche, yet so far this contemporary diversity has not been investigated at a genomic level. In this work, we sequenced the genomes of pairs of randomly selected contemporary isolates sampled from the expectorated sputum of three… CONTINUE READING
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